Welcome to the de Guglielmo Lab!
Overview
Our program focuses on the neural circuits of addiction, with an emphasis on critical molecular and cellular mechanisms that are responsible for adverse behavioral outcomes that are associated with substance abuse and dependence. The de Guglielmo Lab is located in the department of Psychiatry at the UCSD School of Medicine and is part of the Preclinical Addiction Research Consortium (PARC) of UC San Diego
Interests
Drug addiction, Neuropeptides, Dependence, Optogenetics, Pharmacology, Physiology, Neuronal Ensembles, Animal Models, Behavioral Pharmacology
Diversity & Inclusion
The de Guglielmo Lab is committed to creating and sustaining a diverse, accepting, and inclusive research environment. We are dedicated to encouraging participation from underrepresented minority groups. We believe that a diverse research group strengthens science by offering diversity of perspectives, lived experiences, and research interests. We strive to promote diversity through education, mentorship, advocacy, and outreach.
In the news
Opioid dependence found to permanently change brains of rats
Science Daily
January 24, 2020
Approximately one-quarter of patients who are prescribed opioids for chronic pain misuse them, with five to 10 percent developing an opioid use disorder or addiction. In a new study, researchers found that opioid dependence produced permanent changes in the brains of rats.
Cellular atlas of amygdala reveals new treatment target for cocaine addiction
University of California News
October 12, 2023
Researchers at University of California San Diego School of Medicine and the Salk Institute for Biological Studies have created a unique, cell-by-cell atlas of the amygdala, a small structure deep within the brain that plays a crucial role in controlling emotional responses to drugs.
UC San Diego’s Center for Medicinal Cannabis Research Awards Grants for Five Novel Studies
UCSanDiego Health Press Release
October 10, 2019
The Center for Medicinal Cannabis Research (CMCR) at University of California San Diego School of Medicine, the nation’s oldest research center for scientific inquiry into the safety and efficacy of cannabis, has announced $3 million in research grants to explore new applications of cannabis for a number of novel medical applications.
